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Prof. Dr. Dolores Di Vizio | Biochemistry | Best Researcher Award

Professor at Cedars-Sinai Medical Center, United States

Dr. Dolores Di Vizio is a globally recognized physician-scientist whose research has significantly advanced the fields of cancer biology, extracellular vesicles (EVs), and translational oncology. She holds multiple academic positions at Cedars-Sinai Medical Center and plays a leading role in international scientific organizations. Dr. Di Vizio is best known for pioneering the discovery of large oncosomes, a novel type of extracellular vesicle implicated in cancer progression and metastasis.

Publication Profile 

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Educational Background 

  • M.D., University of Naples Federico II, Italy

  • Ph.D., University of Naples Federico II, Italy
    (with postdoctoral training at Harvard Medical School)

Professional Experience 

  • Professor, Departments of Surgery, Pathology & Laboratory Medicine, and Biomedical Sciences
    Cedars-Sinai Medical Center, Los Angeles, CA

  • Co-Director, Cancer Biology Program
    Samuel Oschin Comprehensive Cancer Institute at Cedars-Sinai

  • Visiting Faculty

    • Yonsei University, Korea

    • University of Calabria, Italy

    • IRCCS Regina Elena, Italy

  • Former Faculty,
    Harvard Medical School

  • Editorial and Leadership Roles

    • Deputy Editor, Journal of Extracellular Vesicles (JEV)

    • Editorial Boards: Oncotarget, Biomedicines, Frontiers in Oncology, and others

    • Chair/Organizer: Gordon Research Conferences, ISEV 2021 & 2023

    • Member: NIH TPM Study Section, DoD Prostate Cancer Program, ERC Review Panel

Research Interests 

  • Extracellular Vesicles (EVs) & Large Oncosomes:
    Discovery, molecular profiling, and diagnostic applications.

  • Cancer Metastasis & Progression:
    Mechanisms of tumor dissemination, especially in prostate cancer.

  • Molecular Oncology & Signal Transduction:
    Role of cytoskeletal remodeling and intercellular communication in cancer.

  • Translational Research:
    Development of EV-based diagnostics and therapeutic targets.

Awards and Honors 

  • Over $10 Million in Competitive Research Funding:

    • NIH R01 Grants

    • Department of Defense (DoD)

    • Avon Foundation

    • American Italian Cancer Foundation (AICF)

  • Chair/Co-chair of International Conferences:

    • Gordon Research Conference (2020)

    • ISEV 2021 & 2023

  • Invited Speaker:
    Over 70 national and international institutions, including Nature Webinars, Keystone Symposia, NIH, and AACR.

  • Mentorship Awards and Leadership in Education

    • Mentor for DoD and SPORE programs

    • Participant in NIH T32, R25, and CTSI training programs

Conclusion 

Dr. Dolores Di Vizio is an internationally respected expert in cancer biology and extracellular vesicle research. Her innovative discoveries, particularly in EV biology and cancer metastasis, have earned her global recognition and continuous research support. Her leadership in academic, clinical, and scientific communities, combined with a deep commitment to mentorship and collaboration, makes her one of the most impactful physician-scientists of her generation. She is an ideal candidate for high-level research honors and awards, with a career that exemplifies scientific innovation, translational impact, and educational excellence.

Publications 

  • Ferrara G, Ianniello GP, Di Vizio D, Nappi O. Lymph-node Merkel cell carcinoma with no evidence of cutaneous tumor: report of two cases. Tumori. 1997;83:868–872.


  • Ferrara G, Long M, Di Vizio D. Endometriosis of the appendix: a case report. Minerva Ginecol. 1998;50:389–390.


  • Troncone G, Martinez G, Palombini L, De Rosa G, Mugica C, Rodriguez JA, Zeppa P, Di Vizio D, Lucariello A, Piris MA. Immunocytochemical statement of mdm2 and p21 in invasive cervical cancer: correlation with p53 protein and high-risk HPV. J Clin Pathol. 1998;51:754–760.


  • Insabato L, Di Vizio D, Terracciano LM, Pettinato G. Epithelioid hemangioendothelioma of the breast. Breast. 1999;8:295–297.


  • Insabato L, Di Vizio D, Lambertini M, Bucci L, Pettinato G. Fine needle aspiration cytology of desmoplastic small round cell tumor: a case report. Acta Cytol. 1999;43:641–646.


  • Razani B, Engelman JA, Wang XB, Schubert W, Zhang XL, Marks CB, Macaluso F, Russel RG, Li M, Pestell RG, Di Vizio D, et al. Caveolin-1 null mice are viable but show evidence of hyper-proliferative and vascular abnormalities. J Biol Chem. 2001;276:38121–38138.


  • Pero R, Lembo F, Di Vizio D, Boccia A, Chieffi P, Fedele M, Pierantoni GM, Rossi P, Luliano R, Santoro M, et al. RNF4 is a growth inhibitor expressed in germ cells but not in human testicular tumors. Am J Pathol. 2001;159:1225–1230.


  • Insabato L, Di Vizio D, Terracciano LM, Pettinato G, Staibano S, Bifano D, D’Agostino L. Primary Kaposi sarcoma of the bowel in an HIV-negative patient. J Surg Oncol. 2001;76:197–200.


  • Di Vizio D, Insabato L, Conso G, Zafonte BT, Ferrara G, Pettinato G. Sarcomatoid carcinoma of the colon: report of a case with literature review. Tumori. 2001;87:431–435.


  • Palmieri G, Montella L, Martinetti A, Muto P, Di Vizio D, De Chiara A, La Storia S. Somatostatin analogs and prednisone in advanced refractory thymic tumors. Cancer. 2002;94:1414–1422.


  • Ciacci C, Di Vizio D, Seth R, Insabato G, Mazzacca G, Podolsky DK, Mahida YR. Selective reduction of intestinal trefoil factor in untreated coeliac disease. Clin Exp Immunol. 2002;130:526–531.


  • Pettinato G, Di Vizio D, Manivel JC, Pambuccian SE, Somma P, Insabato L. Solid-pseudopapillary tumor of the pancreas: a neoplasm with distinct and highly characteristic cytological features. Diagn Cytopathol. 2002;27:324–335.


  • Ferrara G, Di Vizio D, Megna AS, Insabato L. Warthin’s tumor: metaplastic changes after fine needle aspiration biopsy. Acta Cytol. 2002;46:442–444.


  • Insabato L, Di Vizio D, Tornillo L, D’Armiento FP, Siciliano A, Milo M, Palmieri G, Pettinato G, Terracciano LM. Clinicopathologic and immunohistochemical study of surgically treated primary gastric MALT lymphoma. J Surg Oncol. 2003;83:106–111.


  • Williams TM, Cheung MWC, Park DS, Razani B, Cohen AW, Muller WJ, Di Vizio D, Chopra NG, Pestell RG, Lisanti MP. Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice (MMTV-PyMT). Mol Biol Cell. 2003;14:1027–1042.


 

 

 

 

Dolores Di Vizio | Biochemistry | Best Researcher Award

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