Professor at Zhejiang University of Technology, China
Dr. Huawei Zhang is a Professor of Microbe Natural Products Chemistry at the School of Pharmaceutical Sciences, Zhejiang University of Technology, China. His research primarily focuses on discovering novel marine microbe-derived biomolecules with therapeutic potential. Over his career, he has published more than 120 peer-reviewed articles with over 4000 citations and holds more than 20 patents in China and the US. His contributions to the field have earned him recognition as one of the World’s Top 2% Scientists in Medicinal & Biomolecular Chemistry from 2021 to 2024.
Publication Profile
Scopus
Orcid
Educational Background 🎓
- B.Sc. in Food Sciences – Northwest A&F University, China (2000)
- M.Sc. in Food Chemistry – Northwest A&F University, China (2003)
- Ph.D. in Natural Products Chemistry – Nanjing University, China (2006)
Professional Experience 💼
- Postdoctoral Fellow, Nanjing University, China (2006–2008)
- Faculty Member, Zhejiang University of Technology, China (Since April 2008)
- Visiting Scholar, Crews Lab, University of California, Santa Cruz, USA (One year)
- Officer on Secondment, National Center of Science & Technology Talents, China (Aug 2015 – Feb 2017)
- Editorial Board Member, Marine Drugs, BMC Microbiology, Current Organic Chemistry
- Professional Committee Member, China Medicinal Fungus Society, China Pharmacology Society
Research Interests 🔬
Dr. Zhang’s research revolves around marine microbial secondary metabolites, including their isolation, structure elucidation, biosynthesis, and therapeutic applications. His primary interests include:
- Marine Microbe-Derived Natural Products
- Secondary Metabolites and Biosynthesis Pathways
- Antibiotic and Cytotoxic Compounds from Marine Microbes
- Structure Elucidation of Bioactive Compounds
Awards and Honors🏆✨
- Named in the World’s Top 2% Scientists List in Medicinal & Biomolecular Chemistry (2021–2024)
- Holds 20+ Chinese and US Patents for microbial-derived bioactive compounds
- Published 120+ peer-reviewed articles with over 4000 citations
Conclusion🌟
Dr. Huawei Zhang is a leading scientist in the field of natural products chemistry, particularly in marine microbial secondary metabolites. His extensive research contributions, numerous publications, and patented discoveries have significantly advanced drug discovery and biosynthetic studies. Through his academic and industrial collaborations, he continues to explore novel bioactive compounds with promising therapeutic applications.
Publications 📚
📄 Article
🧪 Single-crystal structure, Hirshfeld surface and DFT analyses of chrysomycin A, a marine microbe-derived promising agent for anticancer and antimicrobial therapy
✍️ Z. Cai, Zhehui; Z. Hu, Zhe; X. Yao, Xiaojun; P. Liang, Pengyu; H. Zhang, Huawei
📚 Journal of Molecular Structure, 2025
🔗 Citations: 0
📄 Article
💊 Enhancing transdermal delivery of chrysomycin A for the treatment of cutaneous melanoma and MRSA infections using Skin-Penetrating Peptide-Functionalized deformable liposomes
✍️ Y. Cai, Yue; X. Zhang, Xinrui; W. Hu, Wentao; H. Zhang, Huawei; X. Sun, Xuanrong
📚 International Journal of Pharmaceutics, 2025
🔗 Citations: 1
📄 Article
🦠 Intracellular MRSA-targeted lipid-polymer hybrid nanoparticles for macrophage reprogramming and intracellular MRSA eradication
✍️ Y. Cai, Yue; M. Qiao, Meilin; X. Xie, Xiuzhi; H. Zhang, Huawei; X. Sun, Xuanrong
📚 Chemical Engineering Journal, 2025
🔗 Citations: 0
📄 Article
🧬 Overexpression of the Global Transcriptional Regulator LaeA Leads to Production of Cyclic Lipopeptides in Marine-Derived Aspergillus niger L14
✍️ W. Zhou, Wenjuan; M. Li, Mengshi; W. Wang, Wei; X. Bai, Xuelian; H. Zhang, Huawei
📚 Chemistry and Biodiversity, 2025
🔗 Citations: 0
📄 Article
🌿 Green and efficient extraction of an anticancer agent N-methylsansalvamide using ultrasound-assisted deep eutectic solvents from mycelia of strain Fusarium sp. R1
✍️ Y. Bai, Yifan; T. Luo, Tao; Z. Cai, Zhehui; Y. Liu, Yuanyuan; H. Zhang, Huawei
📚 Talanta, 2025
🔗 Citations: 1
📖 Open Access Article
❄️ Unveiling biosynthetic potential of an Arctic marine-derived strain Aspergillus sydowii MNP-2
✍️ Z. Fu, Zhiyang; X. Gong, Xiangzhou; Z. Hu, Zhe; B. Wei, Bin; H. Zhang, Huawei
📚 BMC Genomics, 2024
🔗 Citations: 0
📖 Open Access Article
🧪 Optimization of fermentation conditions and medium components for chrysomycin A production by Streptomyces sp. 891-B6
✍️ Z. Hu, Zhe; Q. Weng, Qiangang; Z. Cai, Zhehui; H. Zhang, Huawei
📚 BMC Microbiology, 2024
🔗 Citations: 0
📖 Open Access Review
🦠 Non-ribosomal peptide synthetase (NRPS)-encoding products and their biosynthetic logics in Fusarium
✍️ Z. Huang, Ziwei; W. Zhu, Wangjie; Y. Bai, Yifan; X. Bai, Xuelian; H. Zhang, Huawei
📚 Microbial Cell Factories, 2024
🔗 Citations: 4
📄 Open Access Article
🧠 Chrysomycin A Reshapes Metabolism and Increases Oxidative Stress to Hinder Glioblastoma Progression
✍️ D. Liu, Dongni; W. Zhang, Wenfang; W. Feng, Wandi; G. Du, Guanhua; Y. Wang, Yuehua
📚 Marine Drugs, 2024
🔗 Citations: 0
📖 Review
🧬 Transcriptional regulators of secondary metabolite biosynthesis in Streptomyces
✍️ X. Pei, Xinwei; Y. Lei, Yunyun; H. Zhang, Huawei
📚 World Journal of Microbiology and Biotechnology, 2024
🔗 Citations: 0