Fan Zhou | Immunology and Microbiology | Research Excellence Award

Dr. Fan Zhou | Immunology and Microbiology | Research Excellence Award

Associate Chief Physician | Nanjing Drum Tower Hospital | China

Dr. Fan Zhou is a clinician-scientist specializing in inflammatory bowel disease and gastric cancer, with a strong focus on the immune microenvironment and tumor immune escape mechanisms. His research integrates molecular immunology with translational medicine to identify pathways that drive cancer progression and inflammation-related disease. He has authored multiple peer-reviewed publications in leading international journals across oncology and immunology. As a principal investigator and contributor to nationally and provincially funded projects, his work advances mechanistic understanding and supports the development of personalized therapeutic strategies with clear clinical relevance.

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Sara Carloni | Biology and Life Sciences | Best Researcher Award

Assist. Prof. Dr. Sara Carloni | Biology and Life Sciences | Best Researcher Award

Assistant Professor at Humanitas University, Italy

Dr. Sara Carloni is an Assistant Professor of Microbiology and Clinical Microbiology at Humanitas University, Italy. Her career spans over a decade of cutting-edge research into microbial pathogenesis, microbiota-host interactions, the gut-brain axis, and antimicrobial resistance (AMR). A pivotal figure in translational microbiology, Dr. Carloni has contributed substantially to both experimental and clinical microbiology. Her breakthrough discovery of a choroid plexus vascular barrier associated with intestinal inflammation, published in Science (2021), has positioned her as a global leader in microbiota and neuroinflammation studies. As a corresponding or leading author on multiple high-impact publications and a frequent speaker at international conferences, she continues to influence the future of biomedical sciences.

Publication Profile 

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Educational Background 🎓

Dr. Sara Carloni has cultivated a robust academic foundation in microbiology and biotechnology through progressive and interdisciplinary training across prestigious institutions. She earned her Bachelor’s degree in Industrial and Environmental Biotechnologies in 2009 from a joint program between Università degli Studi di Milano and Universitat Rovira i Virgili in Spain. She then completed her Master’s degree in Biotechnology at Università degli Studi di Milano in July 2011. Driven by a keen interest in microbial research, she pursued a Ph.D. in Biological and Molecular Sciences with a specialization in Molecular Microbiology, which she completed in May 2015 at Università degli Studi di Milano. Following her doctorate, she engaged in several postdoctoral fellowships: first at Università degli Studi di Milano (2015), focusing on small RNA-mediated mechanisms in Pseudomonas aeruginosa; then at the European Institute of Oncology (2016–2017), investigating microbiota in intestinal and oncologic disorders; and subsequently at Humanitas University (2018–2021), where she delved into the gut-brain axis and intestinal inflammation. Her academic journey culminated in her appointment as Assistant Professor of Microbiology and Clinical Microbiology (RTDA) at Humanitas University in 2021.

Professional Experience 💼

  • Assistant Professor (RTDA)
    Humanitas University (2021–Present)

    • Teaching and research in Microbiology and Clinical Microbiology (MED/07)

    • Supervising PhD and MD students; leading microbiota and AMR research units

  • Postdoctoral Fellow
    Humanitas University (2018–2021)

    • Investigated gut-brain axis, choroid plexus, and intestinal inflammation

  • Postdoctoral Fellow
    European Institute of Oncology (IEO) (2016–2017)

    • Microbiota in IBD and tumorigenesis; explored colitis-brain interaction

  • Postdoctoral Fellow
    Università degli Studi di Milano (2015)

    • Studied quorum sensing and small RNAs in Pseudomonas aeruginosa

Research Interests 🔬

  • Gut-Brain Axis (GBA) and Vascular Barriers

  • Antimicrobial Resistance (AMR)

  • Host-Microbiota Interactions

  • Microbial Metabolites and Neuroinflammation

  • Translational Microbiology

  • Bacterial Extracellular Vesicles (bEVs)

  • Artificial Intelligence in Microbial Diagnostics

Awards and Honors🏆✨

  • Invited Speaker at premier international conferences including:

    • Digestive Disease Week (2024)

    • ECCO Congress (2024)

    • Potsdam Symposium on Mucosal Immunology (2023)

    • IFHNOS World Congress Moderator (2023)

  • Leader of research units in:

    • PNRR-INF-ACT (One Health & AMR Surveillance)

    • PNRR-NBFC (Human Wellbeing & Microbial Biodiversity)

    • 5X1000 Humanitas (IBD and Psychiatric Comorbidities)

  • Visiting Professor, Institut Pasteur – Leadership in microbiota-host interaction and bEVs research

Conclusion🌟

Dr. Sara Carloni stands out as an innovative and collaborative microbiologist, contributing significantly to modern biomedical research. With over 19 peer-reviewed publications, an H-index of 11, and over 1200 citations, she merges basic science discoveries with clinical applications, particularly in AMR surveillance and gut-brain communication. Her multidisciplinary and translational approach places her at the forefront of microbiology, making her a strong contender for high-level research recognitions and global scientific leadership.

Publications 📚

  1. 🍼 Maternal gut microbiota influences immune activation at the maternal-fetal interface affecting pregnancy outcome
    🗞 Nature Communications
    📅 2025-05-09 | 🔗 DOI: 10.1038/s41467-025-58533-8
    👩‍🔬 Contributors: Silvia Giugliano, Andrea Gatti, Martina Rusin, Tilo Schorn, Silvia Pimazzoni, Michela Calanni-Pileri, Valentina Fraccascia, Sara Carloni, Maria Rescigno


  2. 🧫 Epidemiology and resistance profiles of bacteria isolated from blood samples in septic patients at emergency department admission: A 6-year single-centre retrospective analysis from Northern Italy
    🗞 Journal of Global Antimicrobial Resistance
    📅 2025-03 | 🔗 DOI: 10.1016/j.jgar.2024.12.023
    👩‍🔬 Contributors: Valeria Cento, Sara Carloni, Riccardo Sarti, et al.


  3. 🤰 Role of the maternal gut microbiota in immune activation at the maternal-fetal interface: Impact on preeclampsia
    📄 Preprint
    📅 2023-05-30 | 🔗 DOI: 10.21203/rs.3.rs-2845955/v1
    👩‍🔬 Contributors: Maria Rescigno, Silvia Giugliano, Sara Carloni, Tilo Schorn


  4. 🧠 Unveiling the gut-brain axis: Structural and functional analogies between the gut and the choroid plexus vascular and immune barriers
    🗞 Seminars in Immunopathology
    🔗 DOI: 10.1007/S00281-022-00955-3
    👩‍🔬 Contributors: Sara Carloni, Maria Rescigno


  5. 🦠 Gut vascular barrier impairment leads to intestinal bacteria dissemination and colorectal cancer metastasis to liver
    🗞 Cancer Cell
    🔗 DOI: 10.1016/j.ccell.2021.03.004
    👩‍🔬 Contributors: Bertocchi, A., Carloni, S., et al.


  6. 🧠 Identification of a choroid plexus vascular barrier closing during intestinal inflammation
    🗞 Science
    🔗 DOI: 10.1126/science.abc6108
    👩‍🔬 Contributors: Carloni, S., Bertocchi, A., et al.


  7. 🧪 SARS-CoV-2 serology in 4000 health care and administrative staff across seven sites in Lombardy, Italy
    🗞 Scientific Reports
    🔗 DOI: 10.1038/s41598-021-91773-4
    👩‍🔬 Contributors: Sandri, M.T., Carloni, S., et al.


  8. 🧫 Complement C3aR loss drives colorectal cancer by modulating gut microbiota
    🗞 Journal of Immunology
    🔗 WOS: WOS:000589972400485
    👩‍🔬 Contributors: Guglietta, Silvia, Carloni, Sara, et al.


  9. 🦠 Endogenous murine microbiota member Faecalibaculum rodentium and its human homologue protect from intestinal tumour growth
    🗞 Nature Microbiology
    🔗 DOI: 10.1038/s41564-019-0649-5
    👩‍🔬 Contributors: Zagato, E., Carloni, S., et al.


  10. 🧪 IgG serology in health care and administrative staff populations from 7 hospitals representative of different exposures to SARS-CoV-2 in Lombardy, Italy
    📄 medRxiv Preprint
    🔗 DOI: 10.1101/2020.05.24.20111245
    👩‍🔬 Contributors: Sandri, M.T., Carloni, S., et al.


  11. 💩 Therapeutic faecal microbiota transplantation controls intestinal inflammation through IL10 secretion by immune cells
    🗞 Nature Communications
    🔗 DOI: 10.1038/s41467-018-07359-8
    👩‍🔬 Contributors: Burrello, C., Carloni, S., et al.


  12. 🧬 The small RNA ReaL: A novel regulatory element embedded in the Pseudomonas aeruginosa quorum sensing networks
    🗞 Environmental Microbiology
    🔗 DOI: 10.1111/1462-2920.13886
    👩‍🔬 Contributors: Carloni, S., Macchi, R., et al.


  13. 🦠 Post-transcriptional regulation of the virulence-associated enzyme AlgC by the σ²²-dependent small RNA ErsA of Pseudomonas aeruginosa
    🗞 Environmental Microbiology
    🔗 DOI: 10.1111/1462-2920.12590
    👩‍🔬 Contributors: Ferrara, S., Carloni, S., et al.