Assoc. Prof. Dr. Dongwen Wu | Immunology | Best Researcher Award

Associate Professor at Central South University, China

Dr. Dongwen Wu has made impactful contributions in the fields of immunology and gastroenterology, with a total of 30 peer-reviewed publications, including 9 as first or corresponding author. His research has been cited 479 times, earning him an h-index of 12 and an i10-index of 14. His work has appeared in top-tier journals such as Nature Immunology, Science Immunology, and Journal of Experimental Medicine, and has been cited in Nature Reviews Immunology, Science, and Immunity. Dr. Wu’s research focuses on immune cell regulation, mucosal immunity, and the metabolic reprogramming of stromal and immune cells, with applications in inflammation, autoimmunity, and gastrointestinal disorders.

Publication Profile

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Educational Background 

  1. Doctor of Medicine (M.D.)

    • Focus: Clinical Medicine

  2. Doctor of Philosophy (Ph.D.)

    • Institution: Cornell University, Ithaca, NY, USA

    • Field: Likely Immunology or Biomedical Sciences, inferred from research focus and departmental affiliations.

    • Research Focus: Cytokine biology, Th17 cells, mucosal immunity, IL-17 signaling, immune system memory, and fibroblastic reticular cells.

Professional Experience 

  • 2024–2025 – Academic Evaluator, BIOMS 6250, Cornell University

  • 2025–2027 – Appointed Peer Reviewer, International Journal of Gastroenterology (1 of 18 reviewers selected)

  • 2023 – Peer Reviewer, Scientific Reports (PMID: 37635176)

  • 2023 – Peer Reviewer, BMC Cancer (PMID: 37507682)

Dr. Wu has demonstrated leadership and recognition in his field through academic teaching and active peer-review service for internationally recognized journals.

Research Interests 

  • IL-17 signaling and fibroblastic reticular cell (FRC) biology

  • Mucosal immunity and stromal cell–immune cell interactions

  • Metabolic reprogramming in immune and stromal cells

  • Pathogenic Th17 cell function and noncanonical STAT3 activity

  • Dietary impact on immune training and gut inflammation

  • Immunological biomarkers in inflammatory bowel disease (IBD) and cancer

Professional Memberships

  • Member, International Cytokine and Interferon Society (ICIS)

  • Member, American Association of Immunologists (AAI)

  • Member, Youth Scientific Research Club, IBD Committee, Chinese Society of Gastroenterology

Conclusion 

Dr. Dongwen Wu is a distinguished physician-scientist whose multidisciplinary work bridges immunology, gastroenterology, and metabolic research. With high-impact publications and ongoing roles in academic evaluation and peer review, Dr. Wu has established himself as a valuable contributor to the biomedical research community. His insights into stromal–immune interactions and immune training by diet represent novel directions in inflammation and mucosal immunology.

Publications 

  • Wu, D.W., Wang, X., Yang, X., Gu, L., McGeachy, M.J., & Liu, X. (2023).
    Temporary consumption of western diet trains the immune system to reduce future gut inflammation.
    iScience, 26(6), 106915. PMID: 37305694


  • Zhou, J., Cai, T., Wu, D.W., Chen, X., & Wang, F. (2023).
    The role of endoscopic ultrasound-guided fine-needle aspiration/biopsy in the diagnosis of mediastinal lesions.
    Frontiers in Surgery, 9, 1065070. PMID: 36684177


  • Wu, D.W., Poholek, C.H., Majumder, S., Liu, Q., Revu, S.K., Mohib, K., … & McGeachy, M.J. (2021).
    IL-17–dependent fibroblastic reticular cell training boosts tissue protective mucosal immunity through IL-10–producing B cells.
    Science Immunology, 6(66), eaao3669. PMID: 34919443


  • Xiao, Y.#, Wu, D.W.#, Shi, X.#, Liu, S.#, Hu, X., Zhou, C., … & Chen, M. (2021).
    High Child-Pugh and CRUB65 scores predict mortality of decompensated cirrhosis patients with COVID-19: A 23-center, retrospective study.
    Virulence, 12(1), 1199–1208. PMID: 33870852


  • Zhou, C., Wu, D.W., Jawale, C., Li, Y., Biswas, P.S., McGeachy, M.J., & Gaffen, S.L. (2021).
    Divergent functions of IL-17-family cytokines in DSS colitis: Insights from a naturally-occurring human mutation in IL-17F.
    Cytokine, 148, 155715. PMID: 34587561


  • Poholek, C.H., Raphael, I., Wu, D.W., Revu, S., Rittenhouse, N., Uche, U.U., … & McGeachy, M.J. (2020).
    Noncanonical STAT3 activity sustains pathogenic Th17 proliferation and cytokine response to antigen.
    Journal of Experimental Medicine, 217(10). PMID: 32697822


  • Xiao, Y., Shi, X., She, Q., Chen, Q., Pan, H., Zhang, J., Liu, X.J., Wu, H.Y., Jin, W.F., Ke, G., Liu, S.Z., Li, J., Zhou, J., Wu, D.W., … & Chen, M. (2020).
    Exploration of turn-positive RT-PCR results and factors related to treatment outcome in COVID-19: A retrospective cohort study.
    Virulence, 11(1), 1250–1256. PMID: 32921249


  • Majumder, S., Amatya, N., Revu, S., Jawale, C.V., Wu, D.W., Rittenhouse, N., … & McGeachy, M.J. (2019).
    IL-17 metabolically reprograms activated fibroblastic reticular cells for proliferation and survival.
    Nature Immunology, 20(5), 534–545. PMID: 30962593


  • Lin, J., Tan, H., Nie, Y., Wu, D.W., Zheng, W., Lin, W., … & Chen, T. (2019).
    Krüppel‐like factor 2 inhibits hepatocarcinogenesis through negative regulation of the Hedgehog pathway.
    Cancer Science, 110(4), 1220–1231. PMID: 30719823


  • Deng, G., Li, H., Zeng, F., Chen, L., Li, H., Wu, D.W., … & Wang, Z. (2019).
    Pringle maneuver versus hemihepatic blood flow occlusion during hepatectomy: a systematic review and meta-analysis.
    International Journal of Clinical and Experimental Medicine, 12(1), 11–25.


  • Zhang, K., Tian, J., He, Z., Sun, W., Pekbay, B., Lin, Y., Wu, W.D., … & Zhang, L. (2018).
    Validation of the Chinese version of EORTC QLQ‐BN 20 for patients with brain cancer.
    European Journal of Cancer Care, 27(2), e12832. PMID: 29461664


  • Wu, D.W.* Li, Y., & Wang, F. (2017).
    How long can we store blood samples: a systematic review and meta-analysis.
    EBioMedicine, 24, 277–285. PMID: 28965875


  • Li, H.#, Wu, D.W.#, Shi, S., Xu, Y., Wei, L., Liu, J., & Liu, Y. (2017).
    Expression and clinical significance of CD147 in renal cell carcinoma: a meta-analysis.
    Oncotarget, 8(31), 51331. PMID: 28881651


  • Li, H.#, Jiang, C.#, Wu, D.W.#, Shi, S., Liao, M., Wang, J., … & Xu, Z. (2017).
    The prognostic and clinicopathologic characteristics of CD147 and esophagus cancer: A meta-analysis.
    PLoS ONE, 12(7), e0180271. PMID: 28700599


  • Zhang, Z.#, Zhang, X.#, Wei, L.#, Lin, Y.#, Wu, D.W.#, Xie, S., … & Zhang, L. (2017).
    Questionnaire to assess quality of life in patients with breast cancer – validation of the Chinese version of the EORTC QLQ-BR 53.
    The Breast, 32, 87–92. PMID: 28068605


 

 

 

 

Dongwen Wu | Immunology | Best Researcher Award

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